DNA damage response and prostate cancer: defects, regulation and therapeutic implications

DNA damage response (DDR) includes the activation of numerous cellular activities that prevent duplication of DNA lesions and maintain genomic integrity, which is critical for the survival of normal and cancer cells. Specific genes involved in the DDR such as BRCA1/2 and P53 are mutated during prost...

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Vydáno v:Oncogene
Hlavní autoři: Karanika, Styliani, Karantanos, Theodoros, Li, Likun, Corn, Paul G., Thompson, Timothy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333141/
https://ncbi.nlm.nih.gov/pubmed/25132269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.238
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