TGF-β signaling alters the pattern of liver tumorigenesis induced by Pten inactivation

Hepatocarcinogenesis results from the accumulation of genetic and epigenetic changes in liver cells. A common mechanism through which these alterations induce liver cancer is by deregulating signaling pathways. A number of signaling pathways, including the PI3K/PTEN/AKT and transforming growth facto...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Morris, Shelli M., Carter, Kelly T., Baek, Ji Yeon, Koszarek, Amanda, Yeh, Matthew M., Knoblaugh, Sue E., Grady, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333137/
https://ncbi.nlm.nih.gov/pubmed/25132272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.258
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