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The Ubiquitin E3 Ligase SCF-FBXO24 Recognizes Deacetylated Nucleoside Diphosphate Kinase A To Enhance Its Degradation

The Skp-Cul-F box (SCF) ubiquitin E3 ligase machinery recognizes predominantly phosphodegrons or, less commonly, an (I/L)Q molecular signature within substrates to facilitate their recruitment in mediating protein ubiquitination and degradation. Here, we examined the molecular signals that determine...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Chen, Wei, Xiong, Sheng, Li, Jin, Li, Xiuying, Liu, Yuan, Zou, Chunbin, Mallampalli, Rama K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333090/
https://ncbi.nlm.nih.gov/pubmed/25582197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01185-14
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