RET Fusion as a Novel Driver of Medullary Thyroid Carcinoma

INTRODUCTION: Oncogenic RET tyrosine kinase gene fusions and activating mutations have recently been identified in lung cancers, prompting initiation of targeted therapy trials in this disease. Although RET point mutation has been identified as a driver of tumorigenesis in medullary thyroid carcinom...

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Veröffentlicht in:J Clin Endocrinol Metab
Hauptverfasser: Grubbs, Elizabeth G., Ng, Patrick Kwok-Shing, Bui, Jacquelin, Busaidy, Naifa L., Chen, Ken, Lee, Jeffrey E., Lu, Xinyan, Lu, Hengyu, Meric-Bernstam, Funda, Mills, Gordon B., Palmer, Gary, Perrier, Nancy D., Scott, Kenneth L., Shaw, Kenna R., Waguespack, Steven G., Williams, Michelle D., Yelensky, Roman, Cote, Gilbert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
Schlagworte:
Special Features
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333032/
https://ncbi.nlm.nih.gov/pubmed/25546157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-4153
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