Hedgehog signaling stimulates the conversion of cholesterol to steroids

Cholesterol modification of Hedgehog (Hh) ligands is fundamental for the activity of Hh signaling, and cholesterol biosynthesis is also required for intracellular Hh signaling transduction. Here, we investigated the roles and underlying mechanism of Hh signaling in metabolism of cholesterol. The mai...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Tang, Chao, Pan, Yibin, Luo, Huan, Xiong, Wenyi, Zhu, Haibin, Ruan, Hongfeng, Wang, Jirong, Zou, Chaochun, Tang, Lanfang, Ikuchi, Takuma, Long, Fanxin, Wu, Ximei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333021/
https://ncbi.nlm.nih.gov/pubmed/25582983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.01.004
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