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Compound signature detection on LINCS L1000 big data
The Library of Integrated Network-based Cellular Signatures (LINCS) L1000 big data provide gene expression profiles induced by over 10,000 compounds, shRNAs, and kinase inhibitors using the L1000 platform. We developed csNMF, a systematic compound signature discovery pipeline covering from raw L1000...
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| Publicado no: | Mol Biosyst |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4333019/ https://ncbi.nlm.nih.gov/pubmed/25609570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00677a |
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