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Harnessing the biological complexity of Big Data from LINCS gene expression signatures

Gene expression profiling using transcriptional drug perturbations are useful for many biomedical discovery studies including drug repurposing and elucidation of drug mechanisms (MoA) and many other pharmacogenomic applications. However, limited data availability across cell types has severely hinde...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Musa, Aliyu, Tripathi, Shailesh, Kandhavelu, Meenakshisundaram, Dehmer, Matthias, Emmert-Streib, Frank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114505/
https://ncbi.nlm.nih.gov/pubmed/30157183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201937
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