A Phase 2 Study of Epothilone B Analog BMS-247550 (NSC 710428) in Patients With Relapsed Aggressive Non-Hodgkin Lymphomas

BACKGROUND: The management of relapsed aggressive lymphomas remains problematic. Ixabepilone (BMS-247550, epothilone B analog), a potent inhibitor of tubulin disassembly, has promising preclinical and early-phase clinical activity in drug-resistant malignancies. METHODS: This multicenter phase 2 cli...

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Published in:Cancer
Main Authors: Churpek, Jane E., Pro, Barbara, van Besien, Koen, Kline, Justin, Conner, Kathy, Wade, James L., Hagemeister, Fredrick, Karrison, Theodore, Smith, Sonali M.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332882/
https://ncbi.nlm.nih.gov/pubmed/23310949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27917
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