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A Phase 2 Study of Epothilone B Analog BMS-247550 (NSC 710428) in Patients With Relapsed Aggressive Non-Hodgkin Lymphomas
BACKGROUND: The management of relapsed aggressive lymphomas remains problematic. Ixabepilone (BMS-247550, epothilone B analog), a potent inhibitor of tubulin disassembly, has promising preclinical and early-phase clinical activity in drug-resistant malignancies. METHODS: This multicenter phase 2 cli...
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Publié dans: | Cancer |
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Auteurs principaux: | , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332882/ https://ncbi.nlm.nih.gov/pubmed/23310949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27917 |
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