Plant Virus Particles Carrying Tumour Antigen Activate TLR7 and Induce High Levels of Protective Antibody

Induction of potent antibody is the goal of many vaccines targeted against infections or cancer. Modern vaccine designs that use virus-like particles (VLP) have shown efficacy for prophylactic vaccination against virus-associated cancer in the clinic. Here we used plant viral particles (PVP), which...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jobsri, Jantipa, Allen, Alex, Rajagopal, Deepa, Shipton, Michael, Kanyuka, Kostya, Lomonossoff, George P., Ottensmeier, Christian, Diebold, Sandra S., Stevenson, Freda K., Savelyeva, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332868/
https://ncbi.nlm.nih.gov/pubmed/25692288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118096
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