Clinical Validation of KRAS, BRAF, and EGFR Mutation Detection Using Next-Generation Sequencing

OBJECTIVES: To validate next-generation sequencing (NGS) technology for clinical diagnosis and to determine appropriate read depth. METHODS: We validated the KRAS, BRAF, and EGFR genes within the Ion AmpliSeq Cancer Hotspot Panel using the Ion Torrent Personal Genome Machine (Life Technologies, Carl...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Clin Pathol
मुख्य लेखकों: Lin, Ming-Tseh, Mosier, Stacy L., Thiess, Michele, Beierl, Katie F., Debeljak, Marija, Tseng, Li-Hui, Chen, Guoli, Yegnasubramanian, Srinivasan, Ho, Hao, Cope, Leslie, Wheelan, Sarah J., Gocke, Christopher D., Eshleman, James R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332779/
https://ncbi.nlm.nih.gov/pubmed/24838331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1309/AJCPMWGWGO34EGOD
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