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Wilms Tumor Genetics: Mutations in WT1, WTX, and CTNNB1 Account for Only About One-Third of Tumors
Wilms tumor is genetically heterogeneous, and until recently only one Wilms tumor gene was known, WT1 at 11p13. However, WT1 is altered in only ~20% of Wilms tumors. Recently a novel gene, WTX at Xq11.1, was reported to be mutated in Wilms tumors. No overlap between tumors with mutations in WTX and...
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| Publicado no: | Genes Chromosomes Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332772/ https://ncbi.nlm.nih.gov/pubmed/18311776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20553 |
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