Antigen Targeting to Dendritic Cells Allows the Identification of a CD4 T-Cell Epitope within an Immunodominant Trypanosoma cruzi Antigen

Targeting antigens to dendritic cells (DCs) by using hybrid monoclonal antibodies (mAbs) directed against DC receptors is known to improve activation and support long-lasting T cell responses. In the present work, we used the mAb αDEC205 fused to the Trypanosoma cruzi amastigote surface protein 2 (A...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Rampazo, Eline V., Amorim, Kelly N. S., Yamamoto, Marcio M., Panatieri, Raquel Hoffmann, Rodrigues, Mauricio M., Boscardin, Silvia B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332658/
https://ncbi.nlm.nih.gov/pubmed/25679777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117778
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