Antigen Targeting to Dendritic Cells Allows the Identification of a CD4 T-Cell Epitope within an Immunodominant Trypanosoma cruzi Antigen

Targeting antigens to dendritic cells (DCs) by using hybrid monoclonal antibodies (mAbs) directed against DC receptors is known to improve activation and support long-lasting T cell responses. In the present work, we used the mAb αDEC205 fused to the Trypanosoma cruzi amastigote surface protein 2 (A...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rampazo, Eline V., Amorim, Kelly N. S., Yamamoto, Marcio M., Panatieri, Raquel Hoffmann, Rodrigues, Mauricio M., Boscardin, Silvia B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332658/
https://ncbi.nlm.nih.gov/pubmed/25679777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117778
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