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Cycloheximide and Acetoxycycloheximide: Inhibition of Tyrosine Hydroxylase Activity and Amnestic Effects

Mice and rats trained after treatment with cycloheximide or acetoxycycloheximide in a conditioned avoidance response develop an amnesia of their training experience. This amnesia has been attributed to the profound inhibition of protein synthesis caused by the two antibiotics. Evidence is presented...

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Auteurs principaux: Flexner, Louis B., Serota, Roger G., Goodman, Richard H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1973
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC433257/
https://ncbi.nlm.nih.gov/pubmed/4405624
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