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Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing
Schizophrenia (SZ) is a devastating mental disorder afflicting 1% of the population. Recent genome-wide association studies (GWASs) of SZ have identified >100 risk loci. However, the causal variants/genes and the causal mechanisms remain largely unknown, which hinders the translation of GWAS find...
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| Publicat a: | Neurosci Bull |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4332546/ https://ncbi.nlm.nih.gov/pubmed/25575480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-014-1488-2 |
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