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Analysis of Structural Flexibility of Damaged DNA Using Thiol-Tethered Oligonucleotide Duplexes

Bent structures are formed in DNA by the binding of small molecules or proteins. We developed a chemical method to detect bent DNA structures. Oligonucleotide duplexes in which two mercaptoalkyl groups were attached to the positions facing each other across the major groove were prepared. When the d...

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Vydáno v:PLoS One
Hlavní autoři: Fujita, Masashi, Watanabe, Shun, Yoshizawa, Mariko, Yamamoto, Junpei, Iwai, Shigenori
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332495/
https://ncbi.nlm.nih.gov/pubmed/25679955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117798
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