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An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions

For analysis of the main effects of SNPs, meta-analysis of summary results from individual studies has been shown to provide comparable results as “mega-analysis” that jointly analyzes the pooled participant data from the available studies. This fact revolutionized the genetic analysis of complex tr...

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Detalles Bibliográficos
Publicado en:Genet Epidemiol
Main Authors: Sung, Yun Ju, Schwander, Karen, Arnett, Donna K., Kardia, Sharon L.R., Rankinen, Tuomo, Bouchard, Claude, Boerwinkle, Eric, Hunt, Steven C., Rao, Dabeeru C
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332385/
https://ncbi.nlm.nih.gov/pubmed/24719363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21800
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