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CREB1 is a strong genetic predictor of the variation in exercise heart rate response to regular exercise: the HERITAGE Family Study

BACKGROUND: A genome-wide linkage scan identified a quantitative trait locus (QTL) for exercise training-induced changes in submaximal exercise (50W) heart rate (ΔHR50) on chromosome 2q33.3-q34 in the HERITAGE Family Study (N=472). METHODS AND RESULTS: To fine map the region, 1,450 tagSNPs were geno...

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Detalhes bibliográficos
Main Authors: Rankinen, Tuomo, Argyropoulos, George, Rice, Treva, Rao, D.C., Bouchard, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045864/
https://ncbi.nlm.nih.gov/pubmed/20407090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.109.925644
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