Mutagenic DNA Polymerase in Human Leukemic Cells
Evidence is presented that DNA polymerases from human leukemic cells are mutagenic. Nucleic acid-free extracts of acute lymphoblastic leukemic cells polymerized about 10-times more dCTP using poly(dA-dT)·poly(dA-dT) as a template than did extracts from normal lymphocytes. Mutagenic DNA polymerases c...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1973
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4346035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.1.245 |
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