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Double-Stranded RNA as an Inhibitor of Protein Synthesis and as a Substrate for a Nuclease in Extracts of Krebs II Ascites Cells

Concentrations of double-stranded RNA above about 0.1 μg/ml inhibit translation of encephalo-myocarditis viral RNA and mouse globin messenger RNA in extracts of Krebs II ascites cells. Protein synthesis initially proceeds at the control rate, then abruptly shuts off in a manner similar to that obser...

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Detalles Bibliográficos
Main Authors: Robertson, Hugh D., Mathews, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado: 1973
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC433220/
https://ncbi.nlm.nih.gov/pubmed/4346034
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