A high-throughput ChIP-Seq for large-scale chromatin studies

We present a modified approach of chromatin immuno-precipitation followed by sequencing (ChIP-Seq), which relies on the direct ligation of molecular barcodes to chromatin fragments, thereby permitting experimental scale-up. With Bar-ChIP now enabling the concurrent profiling of multiple DNA–protein...

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Bibliografiske detaljer
Udgivet i:Mol Syst Biol
Main Authors: Chabbert, Christophe D, Adjalley, Sophie H, Klaus, Bernd, Fritsch, Emilie S, Gupta, Ishaan, Pelechano, Vicent, Steinmetz, Lars M
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332152/
https://ncbi.nlm.nih.gov/pubmed/25583149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145776
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