Raloxifene Induces Autophagy-Dependent Cell Death in Breast Cancer Cells via the Activation of AMP-Activated Protein Kinase

Raloxifene is a selective estrogen receptor modulator (SERM) that binds to the estrogen receptor (ER), and exhibits potent anti-tumor and autophagy-inducing effects in breast cancer cells. However, the mechanism of raloxifene-induced cell death and autophagy is not well-established. So, we analyzed...

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Publicado no:Mol Cells
Main Authors: Kim, Dong Eun, Kim, Yunha, Cho, Dong-Hyung, Jeong, Seong-Yun, Kim, Sung-Bae, Suh, Nayoung, Lee, Jung Shin, Choi, Eun Kyung, Koh, Jae-Young, Hwang, Jung Jin, Kim, Choung-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332026/
https://ncbi.nlm.nih.gov/pubmed/25537862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.2193
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