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Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells

Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries and identified mefloquine, an anti-malaria medicine, as a potent...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Shin, Ji Hyun, Bae, Dong-Jun, Kim, Eun Sung, Kim, Han Byeol, Park, So Jung, Jo, Yoon Kyung, Jo, Doo Sin, Jo, Dong-Gyu, Kim, Sang-Yeob, Cho, Dong-Hyung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489826/
https://ncbi.nlm.nih.gov/pubmed/26157548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.025
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