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Induction of Cytolysis of Cultured Lymphoma Cells by Adenosine 3′:5′-Cyclic Monophosphate and the Isolation of Resistant Variants

Cultured mouse lymphosarcoma cells are killed on exposure to 0.1 mM N(6),O(2′)-dibutyryl-adenosine 3′:5′-cyclic monophosphate. A population of cells resistant to the killing effect of dibutyryl cyclic AMP at concentrations as high as 1 mM was selected. The growth characteristics of the resistant cel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Daniel, Violet, Litwack, Gerald, Tomkins, Gordon M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4346041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.1.76
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