Inhibition of Reticulocyte Peptide-Chain Initiation by Pactamycin: Accumulation of Inactive Ribosomal Initiation Complexes
Pactamycin does not inhibit the overall initiation factor- and GTP-dependent binding of [(35)S]Met-tRNA(f) to rabbit reticulocyte ribosomes but does prevent the formation of Met-puromycin, provided that the antibiotic is present during the course of the binding reaction. These data indicate that pac...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1973
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4509656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.1.22 |
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