Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine

We have previously generated a mouse model of spontaneous Th2-associated disease of the small intestine called TRAF6ΔDC, in which dendritic cell (DC)-intrinsic expression of the signaling mediator TRAF6 is ablated. Interestingly, broad-spectrum antibiotic treatment ameliorates TRAF6ΔDC disease, impl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Han, Daehee, Walsh, Matthew C., Kim, Kwang Soon, Hong, Sung-Wook, Lee, Junyoung, Yi, Jaeu, Rivas, Gloriany, Surh, Charles D., Choi, Yongwon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331505/
https://ncbi.nlm.nih.gov/pubmed/25689829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118795
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