Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota

Immunoglobulin E (IgE), a key mediator in allergic diseases, is spontaneously elevated in mice with disrupted commensal microbiota such as germ-free (GF) and antibiotics-treated mice. However, the underlying mechanisms for aberrant IgE elevation are still unclear. Here, we demonstrate that food anti...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Hong, Sung-Wook, O, Eunju, Lee, Jun Young, Lee, Minji, Han, Daehee, Ko, Hyun-Ja, Sprent, Jonathan, Surh, Charles D., Kim, Kwang Soon
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531000/
https://ncbi.nlm.nih.gov/pubmed/31131325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw1507
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