Association between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a review

Pseudomonas aeruginosa uses a complex type III secretion system to inject the toxins ExoS, ExoT, ExoU, and ExoY into the cytosol of target eukaryotic cells. This system is regulated by the exoenzyme S regulon and includes the transcriptional activator ExsA. Of the four toxins, ExoU is characterized...

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Bibliographic Details
Published in:Crit Care
Main Authors: Sawa, Teiji, Shimizu, Masaru, Moriyama, Kiyoshi, Wiener-Kronish, Jeanine P
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331484/
https://ncbi.nlm.nih.gov/pubmed/25672496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0668-9
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