Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis

Signal transducer and activator of transcription 5b (STAT5b) is likely the relevant STAT5 isoform with respect to the process of malignant progression in gliomas. STAT5b is a latent cytoplasmic protein involved in cell signaling through the modulation of growth factors, apoptosis, and angiogenesis....

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Bibliographic Details
Published in:Int J Cancer
Main Authors: Gressot, Loyola V., Doucette, Tiffany A., Yang, Yuhui, Fuller, Gregory N., Heimberger, Amy B., Bögler, Oliver, Rao, Arvind, Latha, Khatri, Rao, Ganesh
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331224/
https://ncbi.nlm.nih.gov/pubmed/25302990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29264
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