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Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis

Signal transducer and activator of transcription 5b (STAT5b) is likely the relevant STAT5 isoform with respect to the process of malignant progression in gliomas. STAT5b is a latent cytoplasmic protein involved in cell signaling through the modulation of growth factors, apoptosis, and angiogenesis....

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Detalhes bibliográficos
Publicado no:Int J Cancer
Principais autores: Gressot, Loyola V., Doucette, Tiffany A., Yang, Yuhui, Fuller, Gregory N., Heimberger, Amy B., Bögler, Oliver, Rao, Arvind, Latha, Khatri, Rao, Ganesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331224/
https://ncbi.nlm.nih.gov/pubmed/25302990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29264
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