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N-Heterocyclic Carbene-Catalyzed Enantioselective Annulations: A Dual Activation Strategy for a Formal [4+2] Addition for Dihydrocoumarins

A highly efficient asymmetric formal [4+2] annulation for the synthesis of dihydrocoumarins has been developed via an in situ activated NHC catalysis. Both electrophilic and nucleophilic species are generated in situ simultaneously whereby acyl imidazoles facilitated rapid formation of an NHC-enolat...

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Bibliografische gegevens
Gepubliceerd in:Chem Commun (Camb)
Hoofdauteurs: Lee, Anna, Scheidt, Karl A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331101/
https://ncbi.nlm.nih.gov/pubmed/25623173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc09590a
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