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Imbalanced globin chain synthesis in heterozygous beta-thalassemic bone marrow.

Globin synthesis was studied in the bone marrow of seven heterozygous beta-thalassemic subjects. We found evidence of significant imbalance of alpha- and beta-chain production particularly at short times of incubation. There was a progressive decrease in alpha/beta-chain production ratio with increa...

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Autores principales: Chalevelakis, G, Clegg, J B, Weatherall, D J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1975
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC433094/
https://ncbi.nlm.nih.gov/pubmed/1060068
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