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Therapeutic mechanisms of high-frequency stimulation in Parkinson’s disease and neural restoration via loop-based reinforcement

High-frequency deep brain stimulation (HFS) is clinically recognized to treat parkinsonian movement disorders, but its mechanisms remain elusive. Current hypotheses suggest that the therapeutic merit of HFS stems from increasing the regularity of the firing patterns in the basal ganglia (BG). Althou...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Santaniello, Sabato, McCarthy, Michelle M., Montgomery, Erwin B., Gale, John T., Kopell, Nancy, Sarma, Sridevi V.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330724/
https://ncbi.nlm.nih.gov/pubmed/25624501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406549111
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