Therapeutic mechanisms of high-frequency stimulation in Parkinson’s disease and neural restoration via loop-based reinforcement

High-frequency deep brain stimulation (HFS) is clinically recognized to treat parkinsonian movement disorders, but its mechanisms remain elusive. Current hypotheses suggest that the therapeutic merit of HFS stems from increasing the regularity of the firing patterns in the basal ganglia (BG). Althou...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Santaniello, Sabato, McCarthy, Michelle M., Montgomery, Erwin B., Gale, John T., Kopell, Nancy, Sarma, Sridevi V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330724/
https://ncbi.nlm.nih.gov/pubmed/25624501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406549111
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