Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma

BACKGROUND: In vivo phosphorylation of sphingosine analogs with their ensuing binding and activation of their cell-surface sphingosine-1-phosphate receptors is regarded as the main immunomodulatory mechanism of this new class of drugs. Prophylactic treatment with sphingosine analogs interferes with...

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Dettagli Bibliografici
Pubblicato in:Respir Res
Autori principali: Gendron, David, Lemay, Anne-Marie, Tremblay, Claudine, Lai, Laetitia JA, Langlois, Anick, Bernatchez, Émilie, Flamand, Nicolas, Blanchet, Marie-Renée, Don, Anthony S, Bossé, Ynuk, Bissonnette, Élyse, Marsolais, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330646/
https://ncbi.nlm.nih.gov/pubmed/25645346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0180-z
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