MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer

Development of multidrug resistance (MDR) is an almost universal phenomenon in patients with ovarian cancer, and this severely limits the ultimate success of chemotherapy in the clinic. Overexpression of the MDR1 gene and corresponding P-glycoprotein (Pgp) is one of the best known MDR mechanisms. MD...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Yang, Xiaoqian, lyer, Arun K., Singh, Amit, Choy, Edwin, Hornicek, Francis J., Amiji, Mansoor M., Duan, Zhenfeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330541/
https://ncbi.nlm.nih.gov/pubmed/25687880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08509
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