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Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus

CRISPR-Cas systems are RNA-based immune systems that protect prokaryotes from invaders such as phages and plasmids. In adaptation, the initial phase of the immune response, short foreign DNA fragments are captured and integrated into host CRISPR loci to provide heritable defense against encountered...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Wei, Yunzhou, Chesne, Megan T., Terns, Rebecca M., Terns, Michael P.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330368/
https://ncbi.nlm.nih.gov/pubmed/25589547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1407
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