Transient DNMT1 suppression reveals hidden heritable marks in the genome

Genome-wide demethylation and remethylation of DNA during early embryogenesis is essential for development. Imprinted germline differentially methylated domains (gDMDs) established by sex-specific methylation in either male or female germ cells, must escape these dynamic changes and sustain precise...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: McGraw, Serge, Zhang, Jacques X., Farag, Mena, Chan, Donovan, Caron, Maxime, Konermann, Carolin, Oakes, Christopher C., Mohan, K. Naga, Plass, Christoph, Pastinen, Tomi, Bourque, Guillaume, Chaillet, J. Richard, Trasler, Jacquetta M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330356/
https://ncbi.nlm.nih.gov/pubmed/25578964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1386
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