Wird geladen...
The Dnmt1 Intrinsically Disordered Domain Regulates Genomic Methylation During Development
The DNMT1 cytosine methyltransferase enzyme contains a large ∼300-aa intrinsically disordered domain (IDD) that we previously showed regulated DNA methylation patterns in mouse ES cells. Here we generated seven mouse lines with different mutations in the IDD. Homozygous mutant mice of five lines dev...
Gespeichert in:
| Veröffentlicht in: | Genetics |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2015
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317660/ https://ncbi.nlm.nih.gov/pubmed/25533200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.173609 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|