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Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathway

Ketamine is widely used as an anesthetic, analgesic, or sedative in pediatric patients. We reported that ketamine alters the normal neurogenesis of rat fetal neural stem progenitor cells (NSPCs) in the developing brain, but the underlying mechanisms remain unknown. The PI3K-PKB/Akt (Phosphatidylinos...

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Detalhes bibliográficos
Publicado no:Birth Defects Res B Dev Reprod Toxicol
Main Authors: Dong, Chaoxuan, Rovnaghi, Cynthia R., Anand, KJS
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330101/
https://ncbi.nlm.nih.gov/pubmed/25231110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.21119
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