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Clinical utility of eslicarbazepine: current evidence

Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is blockade of the voltage-gated sodium channel (VGSC). However, in respect to carbamazepine and oxcarbazepine, the active ESL metabolite (eslicarbazepine) affects slow inactivation of VGSC and has a similar affinity...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Des Devel Ther
Päätekijät: Zaccara, Gaetano, Giovannelli, Fabio, Cincotta, Massimo, Carelli, Alessia, Verrotti, Alberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330027/
https://ncbi.nlm.nih.gov/pubmed/25709402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S57409
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