Clinical utility of eslicarbazepine: current evidence

Eslicarbazepine acetate (ESL) is a new antiepileptic drug whose mechanism of action is blockade of the voltage-gated sodium channel (VGSC). However, in respect to carbamazepine and oxcarbazepine, the active ESL metabolite (eslicarbazepine) affects slow inactivation of VGSC and has a similar affinity...

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Bibliografische gegevens
Gepubliceerd in:Drug Des Devel Ther
Hoofdauteurs: Zaccara, Gaetano, Giovannelli, Fabio, Cincotta, Massimo, Carelli, Alessia, Verrotti, Alberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2015
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330027/
https://ncbi.nlm.nih.gov/pubmed/25709402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S57409
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