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Heavier Ions with a Different Linear Energy Transfer Spectrum Kill More Cells Due to Similar Interference with the Ku-Dependent DNA Repair Pathway
Ionizing radiation kills cells mainly due to the generation of DNA double-strand breaks (DSBs). High-linear energy transfer (LET) ionizing radiation induces more cell death and generates a higher relative biological effect (RBE) than low-LET ionizing radiation (such as X or γ ray). Although it is kn...
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| Publicado en: | Radiat Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329976/ https://ncbi.nlm.nih.gov/pubmed/25229976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13857.1 |
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