Distinct Roles of Ape1 Protein, an Enzyme Involved in DNA Repair, in High or Low Linear Energy Transfer Ionizing Radiation-induced Cell Killing

High linear energy transfer (LET) radiation from space heavy charged particles or a heavier ion radiotherapy machine kills more cells than low LET radiation, mainly because high LET radiation-induced DNA damage is more difficult to repair. Relative biological effectiveness (RBE) is the ratio of the...

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Dettagli Bibliografici
Autori principali: Wang, Hongyan, Wang, Xiang, Chen, Guangnan, Zhang, Xiangming, Tang, Xiaobing, Park, Dongkyoo, Cucinotta, Francis A., Yu, David S., Deng, Xingming, Dynan, William S., Doetsch, Paul W., Wang, Ya
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215242/
https://ncbi.nlm.nih.gov/pubmed/25210033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604959
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