ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

ASCL1 is an important regulatory transcription factor in pulmonary neuroendocrine (NE) cell development, but its value as a biomarker of NE differentiation in lung adenocarcinoma (AD) and as a potential prognostic biomarker remains unclear. We examined ASCL1 expression in lung cancer samples of vari...

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Bibliographic Details
Published in:	Oncogene
Main Authors:	Kosari, F, Ida, CM, Aubry, M-C, Yang, L, Kovtun, IV, Klein, JLS, Li, Y, Erdogan, S, Tomaszek, SC, Murphy, SJ, Bolette, LC, Kolbert, CP, Yang, P, Wigle, DA, Vasmatzis, G
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4329973/ https://ncbi.nlm.nih.gov/pubmed/24037524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.359
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ASCL1 and RET expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation

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