Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

BACKGROUND: Increased proliferation of airway smooth muscle (ASM) cells leading to hyperplasia and increased ASM mass is one of the most characteristic features of airway remodelling in asthma. A bioactive lipid, sphingosine-1-phosphate (S1P), has been suggested to affect airway remodelling by stimu...

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Bibliographic Details
Published in:Allergy
Main Authors: Fuerst, E, Foster, H R, Ward, J P T, Corrigan, C J, Cousins, D J, Woszczek, G
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329332/
https://ncbi.nlm.nih.gov/pubmed/25041788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12489
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