Relationship of the first step in protein synthesis to ppGpp: formation of A(5')ppp(5')Gpp.

In the presence of purified Escherichia coli lysyl-tRNA synthetase [L-lysine:tRNALys ligase (AMP-forming) EC 6.1.1.6], L-lysine, and ATP, addition of the nucleotide ppGpp results in formation of a unique product-A(5')ppp(5') Gpp. The same compound is also formed very rapidly in a cell-free...

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Autors principals: Rapaport, E, Svihovec, S K, Zamecnik, P C
Format: Artigo
Idioma:Inglês
Publicat: 1975
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC432828/
https://ncbi.nlm.nih.gov/pubmed/170611
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