Novel Methylated Biomarkers and a Robust Assay to Detect Circulating Tumor DNA in Metastatic Breast Cancer

The ability to consistently detect cell-free tumor-specific DNA in peripheral blood of patients with metastatic breast cancer provides the opportunity to detect changes in tumor burden and to monitor response to treatment. We developed cMethDNA, a quantitative multiplexed methylation-specific PCR as...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Fackler, Mary Jo, Bujanda, Zoila Lopez, Umbricht, Christopher, Teo, Wei Wen, Cho, Soonweng, Zhang, Zhe, Visvanathan, Kala, Jeter, Stacie, Argani, Pedram, Wang, Chenguang, Lyman, Jaclyn P., de Brot, Marina, Ingle, James N., Boughey, Judy, McGuire, Kandace, King, Tari A., Carey, Lisa A., Cope, Leslie, Wolff, Antonio C., Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327879/
https://ncbi.nlm.nih.gov/pubmed/24737128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3392
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