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Effects of 5-azacytidine on natural killer cell activating receptor expression in patients with refractory anemia with excess of blasts

Epigenetic drugs modify DNA methylation and are used in refractory anemia with excess of blasts (RAEB). These drugs may reactivate anti-oncogene expression and restore a normal phenotype instead of inducing antitumor toxicity, although they also have immunosuppressive effects on T-lymphocytes [1] In...

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Dades bibliogràfiques
Publicat a:Leuk Res Rep
Autors principals: Costello, Régis T., Leclercq, Amélie, Treut, Thérèse Le, Sanchez, Carole, Mercier, Delphine, Sébahoun, Gérard
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327760/
https://ncbi.nlm.nih.gov/pubmed/25709892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2014.09.004
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