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Effects of 5-azacytidine on natural killer cell activating receptor expression in patients with refractory anemia with excess of blasts

Epigenetic drugs modify DNA methylation and are used in refractory anemia with excess of blasts (RAEB). These drugs may reactivate anti-oncogene expression and restore a normal phenotype instead of inducing antitumor toxicity, although they also have immunosuppressive effects on T-lymphocytes [1] In...

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Detalhes bibliográficos
Publicado no:Leuk Res Rep
Main Authors: Costello, Régis T., Leclercq, Amélie, Treut, Thérèse Le, Sanchez, Carole, Mercier, Delphine, Sébahoun, Gérard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327760/
https://ncbi.nlm.nih.gov/pubmed/25709892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lrr.2014.09.004
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